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Top 25 VCs for Deep Tech Startups in 2025: A Comprehensive Guide

Top 25 VCs for Deep Tech Startups in 2025: A Comprehensive Guide

The deep tech startup ecosystem is rapidly evolving, and 2025 is anticipated to be an exciting year for entrepreneurs focused on advanced technologies such as AI, blockchain, quantum computing, and more. This list highlights the top 25 venture capital firms that are making significant investments in deep tech startups, helping to shape the future through their targeted funding strategies.
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1. Atlantic Bridge Ventures

Focus: AI, privacy and security, digital health, and deep tech hardware.
Funding: Manages over €500 million in assets.
Notable Portfolio: Movidius (acquired by Intel), Openet, and Decawave.
Stage: Early-stage.
Location: Global, with a presence in Europe and the US.
Learn more about Atlantic Bridge Ventures

2. Fly Ventures

Focus: Early-stage investments in AI, robotics, and frontier technologies.
Funding: €100 million fund dedicated to seed-stage startups.
Notable Portfolio: DeepL, Tatum, and V7 Labs.
Stage: Seed, Pre-Seed.
Location: Germany.
Discover Fly Ventures

3. Voima Ventures

Focus: Deep tech startups in quantum computing, advanced materials, and energy.
Funding: €120 million fund.
Notable Portfolio: IQM Quantum Computers, Polariton Technologies, and Lightricity.
Stage: Early Stage.
Location: Finland.
Learn more about Voima Ventures
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4. Supernova Invest

Focus: Life sciences, cleantech, and digital transformation.
Funding: €250 million under management.
Notable Portfolio: DNA Script, Carbios, and Exotec.
Stage: Early to Growth.
Location: Europe.
Discover Supernova Invest

5. Riot Ventures

Focus: Cybersecurity, AI, and enterprise software.
Funding: €150 million fund.
Notable Portfolio: Darktrace, Snyk, and Tessian.
Stage: Early Stage.
Location: Europe.
Learn more about Riot Ventures

6. Grove Ventures

Focus: Deep tech in AI, IoT, and cybersecurity.
Funding: €200 million fund.
Notable Portfolio: Lightricks, Vayyar Imaging, and Cato Networks.
Stage: Early Stage.
Location: Global.
Learn more about Grove Ventures

7. Walden Catalyst Ventures

Focus: Quantum computing, AI, and semiconductors.
Funding: €300 million fund.
Notable Portfolio: Rigetti Computing, PsiQuantum, and IonQ.
Stage: Early Stage.
Location: Global.
Discover Walden Catalyst Ventures

8. Main Sequence Ventures

Focus: Space tech, biotech, and advanced materials.
Funding: €350 million fund.
Stage: Early Stage.
Location: Australia.
Learn more about Main Sequence Ventures

9. Upheaval Investments

Focus: Deep Tech, Analytics, Privacy and Security, Computing, AI, Mobile, Hardware.
Stage Focus: Pre-Seed, Seed, Series A, Series B, Series C, Growth.
Location: United States.
Discover Upheaval Investments

10. Act Venture Capital

Focus: Deep Tech, Digital Health, Fintech, SaaS, B2B SaaS, Climate Tech, ESG, Agnostic.
Stage Focus: Seed, Series A, Pre-Seed.
Location: Ireland.
Learn more about Act Venture Capital
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11. Good Growth Capital

Focus: Innovative Deep Tech startups with potential for groundbreaking advancements.
Stage Focus: Varies.
Location: Varies.
Discover Good Growth Capital

12. K9 Ventures

Focus: Fostering groundbreaking innovations in Deep Tech.
Stage Focus: Varies.
Location: Varies.
Learn more about K9 Ventures

13. Embark Ventures

Focus: Pioneering breakthrough innovation in Deep Tech fields.
Stage Focus: Varies.
Location: Varies.
Discover Embark Ventures

14. APEX Ventures

Focus: Deep tech and the medical field.
Stage: Early stage.
Sectors: digital platforms, financial technology, insurance technology, Industry 4.0, life sciences, and digital health.
Location: Europe.
Learn more about APEX Ventures

15. SOSV

Focus: Deep tech, planetary health, and human health.
AUM: $1.5 billion+.
Portfolio: 8 unicorn companies.
Stage: Early stage.
Location: Global.
Discover SOSV
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16. Lux Capital

Focus: Early-stage AI, biotech, and neuroscience companies.
Experience: 20+ years of expertise.
AUM: $5B+.
Portfolio: 66 IPOs.
Location: New York.
Learn more about Lux Capital

17. DeepTech Ventures

Focus: Web3 and deep technology.
Stage: Early-stage.
Location: Switzerland.
Discover DeepTech Ventures

18. Verve Ventures

Focus: Technology and science-based startups.
Portfolio: 160+ startups.
Stage: Varies.
Location: Europe.
Learn more about Verve Ventures

19. DCVC (Data Collective)

Focus: Deep-tech.
AUM: $3.5 billion+ invested.
Stage: Seed to Growth.
Location: Global.
Discover DCVC

20. Harpoon Ventures

Focus: AI, deep tech, software infrastructure, and cybersecurity.
Stage: Seed-focused.
Mission: Ensure American technological dominance.
Location: United States.
Learn more about Harpoon Ventures

21. TSVC

Focus: Seed-stage investments in Deeptech, Fintech, SaaS, and Healthtech.
Stage: Seed-stage.
Experience: 12+ years of investing.
Location: United States.
Discover TSVC

22. Bessemer Venture Partners

Focus: AI Startups, ML Startups, Biotech Startups, Deep Tech Startups, Cloud Startups.
AUM: $18 Billion.
Experience: 50 years of investing.
Location: Redwood City, California.
Learn more about Bessemer Venture Partners

23. Sequoia Capital

Focus: Seed-stage startups with large sums of money to help scale.
Stage: Seed to Growth.
Experience: Long track record of success.
Location: Global.
Discover Sequoia Capital

24. Quantonation

Focus: Quantum Computing.
Stage: Early-stage.
Investment Focus: Quantum Technologies.
Location: Global.
Learn more about Quantonation

25. Andreessen Horowitz (a16z)

Focus: Various tech sectors, including deep tech.
Stage: Seed to Growth.
Investment Focus: Tech.
Location: Global.
Discover Andreessen Horowitz
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FAQ

Q: What types of technologies do Atlantic Bridge Ventures invest in?
A: Atlantic Bridge Ventures focuses on AI, privacy and security, digital health, and deep tech hardware. Learn more about Atlantic Bridge Ventures.
Q: Where is Fly Ventures located and what is their investment focus?
A: Fly Ventures is based in Germany and focuses on early-stage investments in AI, robotics, and frontier technologies. Discover more about Fly Ventures.
Q: Who are some notable portfolio companies of Voima Ventures?
A: Notable portfolio companies of Voima Ventures include IQM Quantum Computers, Polariton Technologies, and Lightricity. Learn more about Voima Ventures.
Q: What is the stage focus of Supernova Invest?
A: Supernova Invest invests in early to growth-stage companies, with a focus on life sciences and cleantech. Explore more about Supernova Invest.
Q: What is the focus of Riot Ventures?
A: Riot Ventures focuses on deep tech, specifically in cybersecurity, AI, and enterprise software. Learn more about Riot Ventures.
Q: What is the funding size of Grove Ventures?
A: Grove Ventures manages a fund size of €200 million and focuses on AI, IoT, and cybersecurity sectors. Discover more about Grove Ventures.
Q: Where does Walden Catalyst Ventures primarily invest?
A: Walden Catalyst Ventures primarily invests in early-stage deep tech startups focused on quantum computing, AI, and semiconductors. Learn more about Walden Catalyst Ventures.
Q: What is DCVC's focus area in startup investments?
A: DCVC (Data Collective) focuses on deep-tech startups, investing from seed to growth stages. Discover more about DCVC.
Q: What sectors does Andreessen Horowitz (a16z) invest in?
A: Andreessen Horowitz (a16z) invests across various tech sectors, including deep tech, from seed to growth stages. Learn more about Andreessen Horowitz.

About the Author

Violetta Bonenkamp, also known as MeanCEO, is an experienced startup founder with an impressive educational background including an MBA and four other higher education degrees. She has over 20 years of work experience across multiple countries, including 5 years as a solopreneur and serial entrepreneur.
Violetta is a true multiple specialist who has built expertise in Linguistics, Education, Business Management, Blockchain, Entrepreneurship, Intellectual Property, Game Design, AI, SEO, Digital Marketing, cyber security and zero code automations. Her extensive educational journey includes a Master of Arts in Linguistics and Education, an Advanced Master in Linguistics from Belgium (2006-2007), an MBA from Blekinge Institute of Technology in Sweden (2006-2008), and an Erasmus Mundus joint program European Master of Higher Education from universities in Norway, Finland, and Portugal (2009).
She is the founder of Fe/male Switch, a startup game that encourages women to enter STEM fields, and also leads CADChain, and multiple other projects like the Directory of 1,000 Startup Cities with a proprietary MeanCEO Index that ranks cities for female entrepreneurs. Violetta created the "gamepreneurship" methodology, which forms the scientific basis of her startup game. She also builds a lot of SEO tools for startups. Her achievements include being named one of the top 100 women in Europe by EU Startups in 2022 and being nominated for Impact Person of the year at the Dutch Blockchain Week. She is an author with Sifted and a speaker at different Universities. Recently she published a book on Startup Idea Validation the right way: from zero to first customers and beyond and launched a Directory of 1,500+ websites for startups to list themselves in order to gain traction and build backlinks.
2025-06-04 08:05 Top 25