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Top 25 Accelerators for Deep Tech Startups in North America in 2025

Top 25 Accelerators for Deep Tech Startups in North America in 2025

The startup ecosystem, especially for deep tech startups, is flourishing in North America. With a wide array of accelerators focusing on providing funding, mentorship, and networking opportunities, the journey to scaling a startup can be facilitated through these programs. Here is a curated list of the Top 25 Accelerators for Deep Tech Startups in North America in 2025, including details on their focus areas, funding, mentorship, and unique attributes.
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1. SOSV

Focus: Deep tech, including life sciences (IndieBio), hard tech (HAX), climate tech, and software.
Funding: Offers funding and hands-on support.
Mentorship: Provides mentorship, resources, and a global network of investors.
Global Network: Access to a vast global network of investors and corporate partners.
Assets Under Management: Over $1 billion.
Learn more about SOSV

2. Techstars

Focus: Multiple industries with industry-specific accelerators, including deep tech.
Funding: Provides funding, networking, and mentorship.
Mentorship: Offers hands-on mentorship and access to a large network.
Network: Extensive network of portfolio companies and industry leaders.
Format: Offers in-person and hybrid formats.
Discover Techstars

3. Plug and Play Tech Center

Focus: Sector-specific programs across 40+ industries, including fintech, mobility, healthtech.
Partnerships: Facilitates corporate partnerships for market access and scalability.
Equity: Some programs do not require equity stakes.
Mentorship: Provides mentorship and a global network.
Locations: Silicon Valley, California; Tokyo, Japan; and Alberta, Canada.
Explore Plug and Play Tech Center
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4. Y Combinator (YC)

Focus: Open to all industries, with a strong emphasis on tech startups.
Investment: $500,000 ($125,000 for 7% equity + $375,000 uncapped SAFE).
Program Duration: 3 months.
Benefits: Access to a powerful alumni network, mentorship, and Demo Day exposure.
Location: Mountain View, California.
Visit Y Combinator

5. 500 Global

Focus: Early-stage tech startups, particularly in SaaS and fintech.
Investment: $150,000 (minus the $37,500 program fee) for 6% equity.
Program Duration: 4 months.
Benefits: Founder-focused curriculum, mentorship, and access to a network of 5,000+ founders.
Location: Palo Alto, California.
Learn more about 500 Global

6. AngelPad

Focus: Early-stage tech startups.
Program Length: 10 weeks.
Approach: Boutique accelerator focusing on quality.
Mentorship: Strong mentorship from experienced founders.
Track Record: Ranked as a Top U.S. Accelerator by MIT's Seed Accelerator Benchmark.
Discover AngelPad

7. MassChallenge

Focus: Diverse industries, does not take equity.
Equity: Does not require equity stakes.
Network: Access to a global network.
Locations: Boston, Switzerland, Israel, etc.
Explore MassChallenge

8. Gener8tor

Focus: High-growth potential startups across various sectors.
Program Length: 12-week program.
Support: Funding, mentorship, and individualized coaching.
Ideal For: Tech, consumer products, and health-focused startups.
Locations: Multiple locations across the USA.
Learn more about Gener8tor

9. L-SPARK

Focus: SaaS startups.
Support: Funding, mentorship, and industry connections.
Partnerships: Strong corporate partnerships, including BlackBerry and TELUS.
Location: Ottawa, Canada.
Discover L-SPARK

10. RaiseIQ by DevSquad

Focus: Vertical B2B SaaS startups.
Support: $500,000 in development services, prototyping, and up to $500,000 in partner perks.
Program Length: 18 months.
Location: Salt Lake City, UT, USA (with in-person and remote options available).
Learn more about RaiseIQ
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11. DMZ

Focus: Tech startups.
Support: Connections to customers, capital, experts, and a community of entrepreneurs.
Ranking: Ranked as the #1 university-based business incubator in the world by UBI Global.
Location: Canada.
Explore DMZ

12. HighTechXL

Focus: High-tech startups, including deep tech, medtech, and energy.
Support: Dedicated support in prototyping, scaling, and market entry.
Location: Eindhoven, Netherlands.
Discover HighTechXL

13. Startupbootcamp

Focus: Deep tech and robotics.
Support: Hands-on mentorship from 100+ industry experts, seed funding, and access to a global and local network.
Program Length: 3 months.
Learn more about Startupbootcamp

14. RocketSpace

Focus: Wide range of technology sectors, including Foodtech, Mobility Tech, Agtech, and Logistics Tech.
Program Length: 6-month program.
Cohorts: Two cohorts per year.
Explore RocketSpace

15. NVIDIA Inception Program

Focus: AI and data science sectors.
Support: Product development, prototyping, deployment, marketing assistance, training, workshops, mentorship, and networking.
Founded: 1993.
Visit NVIDIA Inception Program
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16. MaRS Discovery District

Focus: Multiple sectors, including enterprise applications and high tech.
Portfolio Count: 267 companies.
Location: Canada.
Learn more about MaRS Discovery District

17. Launch Ventures

Focus: Enterprise Applications, Food, and Agriculture Tech.
Portfolio Count: 27.
Location: Canada, United States.
Explore Launch Ventures

18. Bioindustrial Innovation Canada

Focus: Wide range of technologies and sectors.
Funding: $150 M in funding.
Location: Canada.
Discover Bioindustrial Innovation Canada

19. Launch Academy

Focus: Tech startups.
Support: Working space and services through a monthly rental membership.
Mentorship: Mentored over 500 startups.
Location: Canada.
Learn more about Launch Academy

20. TechAlliance

Focus: Innovative businesses and startups.
Portfolio Count: 110.
Location: Canada.
Explore TechAlliance

21. Polsky Deep Tech Ventures

Focus: Translating innovations into startups.
Support: Full-spectrum accelerator and venture support initiative.
Location: University of Chicago.
Visit Polsky Deep Tech Ventures

22. Duality

Focus: Quantum startups.
Type: Accelerator program focused on quantum startups.
Location: US.
Learn more about Duality

23. Next Canada

Focus: Entrepreneurship and innovation.
Location: Canada.
Explore Next Canada

24. Google for Startups Canada

Focus: Early-stage startups.
Support: Mentorship and resources.
Location: Canada.
Learn more about Google for Startups Canada

25. University of Waterloo Velocity Incubator

Focus: University-based startup incubator.
Location: Canada.
Discover University of Waterloo Velocity Incubator
Additional Accelerators of Note:
Important Considerations:
  • Focus Area: Choose an accelerator that aligns with your specific deep tech area (e.g., AI, biotech, hardware, etc.).
  • Stage of Startup: Some accelerators are best for very early-stage startups, while others are better for companies that are a bit more developed.
  • Location: Consider whether you prefer in-person, remote, or hybrid programs.
  • Equity & Funding: Review the funding terms and equity requirements of each program carefully.
  • Network: Evaluate the strength and relevance of the accelerator's network.
  • Mentorship: Look for accelerators that provide hands-on mentorship from experienced entrepreneurs and industry experts.
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FAQ

Q: Which accelerator focuses on diverse industries without taking equity?
A: MassChallenge is focused on diverse industries and does not take equity. Learn more about MassChallenge.
Q: What accelerator offers a $500,000 investment for tech startups?
A: Y Combinator (YC) provides an investment of $500,000 to tech startups. Discover Y Combinator.
Q: Which accelerator has strong corporate partnerships including BlackBerry and TELUS?
A: L-SPARK has strong partnerships with companies like BlackBerry and TELUS. Explore L-SPARK.
Q: Where can SaaS startups find specialized support and funding?
A: Gener8tor focuses on high-growth potential startups including SaaS. Learn more about Gener8tor.
Q: Which accelerator is known for prototyping, scaling, and market entry support for high-tech startups?
A: HighTechXL offers dedicated support in these areas. Find out more about HighTechXL.
Q: What accelerator program is focused on quantum startups in the United States?
A: Duality focuses specifically on quantum startups. Discover Duality.
Q: Which university-based incubator has been ranked #1 by UBI Global?
A: DMZ was ranked as the #1 university-based business incubator in the world by UBI Global. Learn more about DMZ.
Q: What is the focus area of the RaiseIQ by DevSquad accelerator?
A: RaiseIQ by DevSquad is focused on vertical B2B SaaS startups. Explore RaiseIQ by DevSquad.
Q: Which accelerator provides AI and data science startups with product development and prototyping support?
A: NVIDIA Inception Program offers extensive support to AI and data science startups. Find out more about NVIDIA Inception Program.
Q: Where can early-stage tech startups receive $150,000 for 6% equity?
A: 500 Global provides $150,000 for 6% equity to early-stage tech startups. Learn more about 500 Global.

About the Author

Violetta Bonenkamp, also known as MeanCEO, is an experienced startup founder with an impressive educational background including an MBA and four other higher education degrees. She has over 20 years of work experience across multiple countries, including 5 years as a solopreneur and serial entrepreneur.
Violetta is a true multiple specialist who has built expertise in Linguistics, Education, Business Management, Blockchain, Entrepreneurship, Intellectual Property, Game Design, AI, SEO, Digital Marketing, cyber security and zero code automations. Her extensive educational journey includes a Master of Arts in Linguistics and Education, an Advanced Master in Linguistics from Belgium (2006-2007), an MBA from Blekinge Institute of Technology in Sweden (2006-2008), and an Erasmus Mundus joint program European Master of Higher Education from universities in Norway, Finland, and Portugal (2009).
She is the founder of Fe/male Switch, a startup game that encourages women to enter STEM fields, and also leads CADChain, and multiple other projects like the Directory of 1,000 Startup Cities with a proprietary MeanCEO Index that ranks cities for female entrepreneurs. Violetta created the "gamepreneurship" methodology, which forms the scientific basis of her startup game. She also builds a lot of SEO tools for startups. Her achievements include being named one of the top 100 women in Europe by EU Startups in 2022 and being nominated for Impact Person of the year at the Dutch Blockchain Week. She is an author with Sifted and a speaker at different Universities. Recently she published a book on Startup Idea Validation the right way: from zero to first customers and beyond and launched a Directory of 1,500+ websites for startups to list themselves in order to gain traction and build backlinks.
2025-06-07 08:17 Top 25