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Top 25 Angel Investors for Deeptech Startups in 2025

Top 25 Angel Investors for Deeptech Startups in 2025

As deeptech continues to advance rapidly, angel investors play a crucial role in supporting innovations that could shape future industries. This article highlights the top 25 angel investors for deeptech startups in 2025, detailing their investment focus, notable contributions, and influence within the sector.
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1. Marc Andreessen

Focus: AI and Health Tech
Profile: A co-founder of Andreessen Horowitz and a pioneer in Silicon Valley, he has actively backed deeptech startups like OpenAI and Oculus VR.
Notable Contributions: Beyond investing, he provides vital mentorship and operational support to startups, emphasizing software and application of deep tech.
Learn more about Marc Andreessen

2. Amit Karp

Focus: Health Diagnostics and AI
Profile: A seasoned venture capitalist at Bessemer Venture Partners, Karp is known for his investments in Clarity and other healthtech innovations.
Notable Contributions: Karp focuses on addressing healthcare challenges through AI and deeptech solutions.
Discover Amit Karp's work

3. Daniel Ek

Focus: AI and Media
Profile: Co-founder and CEO of Spotify, Ek has invested in various startups, focusing on those at the intersection of technology and culture.
Notable Contributions: His insights from building a successful tech platform are invaluable for audio and content-based deeptech startups.
Explore Daniel Ek's initiatives
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4. Naval Ravikant

Focus: Emerging Technologies
Profile: A well-known angel investor with a portfolio that includes Uber and Postmates, Ravikant emphasizes on early-stage tech innovations.
Notable Contributions: Focused on mentoring entrepreneurs and fostering innovative ideas within deeptech.
Learn about Naval Ravikant

5. Peter Thiel

Focus: AI, Fintech, and Biotech
Profile: Co-founder of PayPal and Facebook investor, Thiel is one of the most influential angel investors in Silicon Valley.
Notable Contributions: Committed to investing in disruptive technologies that challenge traditional norms.
Discover more about Peter Thiel

6. Chris Sacca

Focus: Renewable Energy and Internet Technologies
Profile: Founder of Lowercase Capital and an early investor in Twitter, Sacca focuses on groundbreaking technologies that offer scalability.
Notable Contributions: Known for investing in transformative tech projects and future-forward businesses.
Explore Chris Sacca's portfolio

7. Ron Conway

Focus: Broad Technology Investments
Profile: A renowned angel investor and founder of SV Angel, Conway has positioned himself as a crucial supporter of early-stage tech companies.
Notable Contributions: He is known for his extensive network and mentorship in aiding startup growth.
Learn more about Ron Conway

8. Esther Dyson

Focus: Health and Biotechnology
Profile: An early investor in health and technology companies, Dyson emphasizes the importance of ethics in deeptech.
Notable Contributions: Influential advocate for technology that benefits societal well-being and sustainable development.
Discover Esther Dyson's impact

9. Bill Gates

Focus: Health Technologies and Clean Energy
Profile: The co-founder of Microsoft and renowned philanthropist, Gates invests heavily in technologies that aim to solve health and sustainability challenges.
Notable Contributions: His involvement extends beyond financial support, as he actively promotes responsible tech innovation.
Learn more about Bill Gates

10. Diane Greene

Focus: Cloud Computing and AI
Profile: Co-founder of VMware and former CEO of Google Cloud, Greene invests in companies that leverage data-driven technologies.
Notable Contributions: Greene supports startups seeking to innovate within the cloud space.
Explore Diane Greene's journey
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11. Sam Altman

Focus: AI and Software Development
Profile: CEO of OpenAI and former president of Y Combinator, Altman actively invests in startups that push the boundaries of AI and data science.
Notable Contributions: Advocates for responsible AI development and nurturing talent in deeptech.
Learn more about Sam Altman

12. Michael Seibel

Focus: Technology and Entrepreneurship
Profile: CEO of Y Combinator and investor in startups, Seibel emphasizes mentorship in developing early-stage tech companies.
Notable Contributions: Works closely with founders to refine their products and develop robust business models.
Discover Michael Seibel's work

13. Katherine Boyle

Focus: Aerospace, Defense, and Robotics
Profile: A partner at General Catalyst, Boyle is focused on investing in next-gen aerospace and defense technologies.
Notable Contributions: Emphasizes innovation in sectors that enhance national security and technology.
Learn about Katherine Boyle

14. Ali Partovi

Focus: Blockchain and Tech Innovation
Profile: Co-founder of Code.org and an early investor in several tech companies, Partovi promotes educational technology and blockchain startups.
Notable Contributions: Advocates for accessibility and innovation in education and technology sectors.
Discover Ali Partovi's insights

15. Cathy Hackl

Focus: VR/AR and Mixed Technologies
Profile: Known as a "Godmother of the Metaverse," Hackl invests in companies that advance virtual and augmented reality solutions.
Notable Contributions: Advocates for diversity in tech and the vital role of immersive experiences.
Learn more about Cathy Hackl
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16. Marcelo Claure

Focus: Telecommunications and Smart Technologies
Profile: Executive chairman at WeWork and former CEO of Sprint, Claure invests in telecom and tech companies that innovate connectivity.
Notable Contributions: Supports growth in telecommunications that enhance global access to technology.
Discover Marcelo Claure

17. Ramy Youssef

Focus: Social Impact and Tech-driven Solutions
Profile: Comedian and entrepreneur, Youssef invests in diverse startups addressing social issues through technology.
Notable Contributions: Encourages initiatives that use tech for positive societal change.
Learn about Ramy Youssef's initiatives

18. Naval S. E. S. K. Sethi

Focus: Advanced Manufacturing and Robotics
Profile: Angel investor and founder of various tech firms, Sethi focuses on startups that leverage robotics for manufacturing.
Notable Contributions: Promotes innovations in production efficiency and sustainability.
Discover insights from Naval Sethi

19. Josh Wolfe

Focus: Biotech and Energy
Profile: Co-founder of Lux Capital, Wolfe invests in deeptech focused on biotech and energy solutions.
Notable Contributions: Bridges the gap between academic innovation and commercial viability.
Learn more about Josh Wolfe

20. April Underwood

Focus: Communication Technologies
Profile: Former head of product at Slack, Underwood invests in companies that innovate communication and collaboration.
Notable Contributions: Focuses on enhancing workplace connectivity and efficiency through technology.
Explore April Underwood's impact

21. Cynthia Breazeal

Focus: Robotics and Human-AI Interaction
Profile: Founding director of the Personal Robots Group at MIT, Breazeal invests in startups focused on consumer robotics.
Notable Contributions: Advocates for human-centered robotics that enhance daily living.
Learn about Cynthia Breazeal's work

22. Patrick McKenzie

Focus: SaaS and Network Technologies
Profile: A founder and investor known for his expertise in SaaS solutions, McKenzie focuses on network-driven startups.
Notable Contributions: His insights help tech companies scale effectively in their respective markets.
Discover Patrick McKenzie

23. Benedict Evans

Focus: Tech Strategy and Market Dynamics
Profile: A tech strategist and investor, Evans invests in companies innovating within market dynamics and technology trends.
Notable Contributions: Recognized for his analysis and commentary on the future of tech.
Explore Benedict Evans's insights

24. Tracy Chou

Focus: Diversity in Tech and Innovations
Profile: A pioneer for women in tech, Chou invests in startups that advocate for diversity and innovative tech solutions.
Notable Contributions: Focuses on creating inclusive environments within tech industries.
Learn about Tracy Chou's advocacy

25. Jeff Clavier

Focus: Seed-Stage Tech Investments
Profile: Founder of Uncork Capital, Clavier specializes in seed-stage investments in software and deeptech solutions.
Notable Contributions: A hands-on investor committed to the growth of startups, emphasizing product-market fit.
Discover Jeff Clavier's work
Each of these angel investors plays a significant role in nurturing the next generation of deeptech startups, bringing not only funding but also invaluable experience and mentorship.
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FAQ

Q: Who are some of the top angel investors in deep tech as of 2025?
A: Notable angel investors include Marc Andreessen, Amit Karp, and Daniel Ek, who are known for their significant investments in AI, machine learning, and health diagnostics. Learn more from Waveup.
Q: How much is the European Innovation Council investing in deep tech in 2025?
A: The European Innovation Council plans to invest €1.4 billion in deep tech throughout 2025, focusing on various advanced technologies. Find out more from Sifted.
Q: What types of technologies are attracting the most investments in deep tech?
A: Investments are being heavily directed towards sectors like quantum computing, clean energy, biotechnologies, and advanced materials. Read more on biforesight.com.
Q: What is the significance of the EIC STEP Scale-up Scheme?
A: The EIC STEP Scale-up Scheme allocates €300 million aimed at helping deep tech companies scale, with individual investments ranging from €10 million to €30 million. Learn more from Shaping Europe's digital future.
Q: How many deep tech investors were listed by NFX?
A: NFX highlighted an extensive list featuring 1364 Deep Tech seed investors that emphasizes community-driven recommendations. Discover the list from NFX.
Q: What regions are seeing increased venture capital activity in deep tech?
A: Europe, particularly, is experiencing an influx of venture capital in deep tech, especially through organizations like EIC and regional investors in the CEE and DACH areas. Find out more from The Recursive.
Q: What role do universities play in deep tech investments?
A: Universities are crucial in the development of deep tech innovations, serving as incubators for new technologies and opportunities for strategic investment. Read more on Capboard.
Q: How are budgets allocated for research and development in deep tech in the UK?
A: The UK government has allocated £20.4 billion for research and development, aiming to bolster deep tech innovation and scale-ups. Learn more on biforesight.com.
Q: Which angel investors are mentioned in the top lists for deep tech?
A: Top angel investors in the tech space include Naval Ravikant, Peter Thiel, and Ashton Kutcher, who are noted for their contributions and investments in various tech startups. Check the full list from rocketdevs.com.
Q: What is the focus of the top deep tech venture capital firms in 2025?
A: Leading deep tech venture capital firms primarily invest in sectors including AI, machine learning, biotech innovations, and resource-efficient technologies. Explore more through Sifted.

About the Author

Violetta Bonenkamp, also known as MeanCEO, is an experienced startup founder with an impressive educational background including an MBA and four other higher education degrees. She has over 20 years of work experience across multiple countries, including 5 years as a solopreneur and serial entrepreneur.
Violetta is a true multiple specialist who has built expertise in Linguistics, Education, Business Management, Blockchain, Entrepreneurship, Intellectual Property, Game Design, AI, SEO, Digital Marketing, cyber security and zero code automations. Her extensive educational journey includes a Master of Arts in Linguistics and Education, an Advanced Master in Linguistics from Belgium (2006-2007), an MBA from Blekinge Institute of Technology in Sweden (2006-2008), and an Erasmus Mundus joint program European Master of Higher Education from universities in Norway, Finland, and Portugal (2009).
She is the founder of Fe/male Switch, a startup game that encourages women to enter STEM fields, and also leads CADChain, and multiple other projects like the Directory of 1,000 Startup Cities with a proprietary MeanCEO Index that ranks cities for female entrepreneurs. Violetta created the "gamepreneurship" methodology, which forms the scientific basis of her startup game. She also builds a lot of SEO tools for startups. Her achievements include being named one of the top 100 women in Europe by EU Startups in 2022 and being nominated for Impact Person of the year at the Dutch Blockchain Week. She is an author with Sifted and a speaker at different Universities. Recently she published a book on Startup Idea Validation the right way: from zero to first customers and beyond and launched a Directory of 1,500+ websites for startups to list themselves in order to gain traction and build backlinks.
2025-06-04 08:12 Top 25