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2025-04-22 08:42 Top 10

Top 10 Incubators for Deep Tech Startups in North America in 2025

Top 10 Incubators for Deep Tech Startups in North America in 2025

The deep tech landscape is rapidly evolving, and by 2025, several incubators and accelerators are expected to play pivotal roles in nurturing innovative startups. These specialized programs offer crucial resources ranging from funding to mentorship, tailored specifically for companies focused on advanced technology sectors such as AI, biotechnology, and quantum computing. Here is a detailed look at the Top 10 Incubators for Deep Tech Startups in North America in 2025.
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1. SOSV

Location: Princeton, New Jersey (Global Presence)
Description: SOSV is a leading global venture capital firm known for its strong focus on deep tech, human health, and planetary health. With assets under management totaling $1.3 billion, it boasts an impressive portfolio of eight unicorn companies. SOSV emphasizes comprehensive support beyond just funding, offering early-stage startups invaluable feedback, resources, and growth strategies.
Key Features: Active investment strategy, a network of resources, and an early-stage focus.
Learn more about SOSV

2. Alumni Ventures Deep Tech Fund

Location: Manchester, New Hampshire
Description: This VC is recognized for its diversified investment portfolio centered around deep technology, actively investing in 15-20 companies monthly. With over 1,000 portfolio companies and more than $1 billion raised, the Alumni Ventures Deep Tech Fund is one of the most prolific venture funds worldwide, supporting firms from seed to late-stage.
Key Features: Third most active VC globally and a broad investment spectrum.
Discover Alumni Ventures Deep Tech Fund
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3. Techstars

Location: Multiple Locations across North America
Description: Techstars operates a 3-month incubator program designed to guide entrepreneurs through product-market fit, traction, and capital acquisition. It has a proven mentor network and offers over 50 programs globally, ensuring that startups receive personalized attention in smaller class sizes to enhance their success.
Key Features: Access to an extensive global network and hands-on mentorship.
Explore Techstars

4. Y Combinator (YC)

Location: Mountain View, California
Description: Y Combinator is renowned for its successful track record, having funded over 4,000 startups, including giants like Airbnb and Stripe. The program provides a three-month immersive experience, offering $500,000 in funding for a 7% equity stake, along with unparalleled access to mentors and a powerful alumni network.
Key Features: Extensive mentorship, access to top investors during Demo Day, and a robust alumni community.
Learn more about Y Combinator

5. Plug and Play Tech Center

Location: Sunnyvale, California
Description: Plug and Play offers industry-specific programs focusing on driving innovation through corporate partnerships. Operating across 40+ sectors, it combines access to coworking spaces with tailored mentorship and networking opportunities, providing venture funding to startups, often without taking equity.
Key Features: Diverse sector programs and a collaborative environment.
Discover Plug and Play Tech Center
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6. Data Collective (DCVC)

Location: Palo Alto and San Francisco, California
Description: DCVC targets seed, series A, and growth-stage companies focusing on transformative technologies in fields like climate tech, AI, and cybersecurity. With $725 million raised and 469 investments made, DCVC aims to back companies that can drastically reshape industries through their innovations.
Key Features: Strong focus on transformative companies and impressive exit rates.
Learn more about Data Collective

7. Google for Startups Accelerator

Location: Multiple Locations in North America
Description: Google for Startups provides equity-free technical support alongside mentoring from Google product and engineering teams. Startups benefit from tailored bootcamps, access to Google's vast network, and assistance on various strategic aspects of their businesses.
Key Features: Equity-free support and extensive Google resources.
Discover Google for Startups Accelerator

8. AngelPad

Location: New York, NYC & Other Locations
Description: Recognized as a top U.S. accelerator by MIT's Seed Accelerator Benchmark, AngelPad is a highly selective program that runs a ten-week mentorship-driven initiative. It nurtures early-stage startups to help them achieve product-market fit and initial validation across numerous tech verticals.
Key Features: High-rank accolades and an intensive mentorship model.
Learn more about AngelPad

9. MassChallenge

Location: Multiple Locations including Boston, Massachusetts
Description: MassChallenge is a global network that supports early-stage entrepreneurs with high impact potential. By providing access to investors, mentorship, and additional resources, this accelerator helps startups with global ambitions grow and scale effectively.
Key Features: A worldwide network of resources and a supportive community.
Explore MassChallenge

10. Polsky Deep Tech Ventures

Location: University of Chicago
Description: Polsky is dedicated to transforming innovations into startups focused on deep tech. Its unique program, Duality, targets quantum technologies, making it the first accelerator in the U.S. to provide this focused level of support for quantum startups.
Key Features: Specialization in deep tech and strong university support.
Learn more about Polsky Deep Tech Ventures
This compilation of the top incubators for deep tech startups reflects a dynamic environment where innovative ideas are transformed into impactful businesses, equipped with the necessary resources and support to thrive.
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FAQ

Q: What are some of the top incubators for deep tech startups in North America for 2025?
A: The top incubators include SOSV, Alumni Ventures Deep Tech Fund, Techstars, Y Combinator, Plug and Play Tech Center, and more. Learn more about these incubators.
Q: What kind of support does SOSV provide to startups?
A: SOSV offers funding, feedback, resources, and growth strategies with a focus on early-stage startups in sectors like planetary health and human health. Explore SOSV's offerings.
Q: How does Techstars assist entrepreneurs?
A: Techstars provides a 3-month program focused on achieving product-market fit, access to a global network of investors, and personalized mentorship. Discover Techstars.
Q: What unique advantages does Y Combinator offer?
A: Y Combinator provides substantial funding, access to a powerful alumni network, and exposure to top investors during its 3-month program. Find out more about Y Combinator.
Q: Can I participate in Plug and Play Tech Center without giving up equity?
A: Yes, Plug and Play Tech Center offers venture funding without equity in certain cases, providing tailored mentorship and access to industry-specific programs. Learn more about Plug and Play.
Q: What sectors does Data Collective (DCVC) focus on?
A: Data Collective invests in diverse sectors, including climate, crypto, cybersecurity, aerospace, and AI. They focus on transformative deep tech companies. Explore DCVC's investment areas.
Q: What support does Google for Startups Accelerator provide?
A: The accelerator offers equity-free support, technical bootcamps, dedicated mentoring from Google experts, and guidance on product strategy. Learn more about Google for Startups.
Q: What is the focus of AngelPad?
A: AngelPad is a boutique accelerator emphasizing quality, offering a 10-week program that helps startups find product-market fit and obtain validation. Find out more about AngelPad.
Q: How does MassChallenge support early-stage entrepreneurs?
A: MassChallenge provides high-impact early-stage entrepreneurs with access to a global network of investors, mentors, and resources to accelerate their growth. Discover more about MassChallenge.
Q: What distinguishes Polsky Deep Tech Ventures from other accelerators?
A: Polsky focuses specifically on deep tech ventures and offers support for innovative quantum startups through its unique accelerator program, Duality. Learn more about Polsky's initiatives.

About the Author

Violetta Bonenkamp, also known as MeanCEO, is an experienced startup founder with an impressive educational background including an MBA and four other higher education degrees. She has over 20 years of work experience across multiple countries, including 5 years as a solopreneur and serial entrepreneur.
Violetta is a true multiple specialist who has built expertise in Linguistics, Education, Business Management, Blockchain, Entrepreneurship, Intellectual Property, Game Design, AI, SEO, Digital Marketing, cyber security and zero code automations. Her extensive educational journey includes a Master of Arts in Linguistics and Education, an Advanced Master in Linguistics from Belgium (2006-2007), an MBA from Blekinge Institute of Technology in Sweden (2006-2008), and an Erasmus Mundus joint program European Master of Higher Education from universities in Norway, Finland, and Portugal (2009).
She is the founder of Fe/male Switch, a startup game that encourages women to enter STEM fields, and also leads CADChain, and multiple other projects like the Directory of 1,000 Startup Cities with a proprietary MeanCEO Index that ranks cities for female entrepreneurs. Violetta created the "gamepreneurship" methodology, which forms the scientific basis of her startup game. She also builds a lot of SEO tools for startups. Her achievements include being named one of the top 100 women in Europe by EU Startups in 2022 and being nominated for Impact Person of the year at the Dutch Blockchain Week. She is an author with Sifted and a speaker at different Universities. Recently she published a book on Startup Idea Validation the right way: from zero to first customers and beyond and launched a Directory of 1,500+ websites for startups to list themselves in order to gain traction and build backlinks.