Top 25 Incubators for AI Startups in South America in 2025
South America continues to nurture some of the most promising AI startups, thanks to various incubator and accelerator programs. Here is a detailed list of the top 25 incubators and accelerators for AI startups in South America for 2025.
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1. 500 Startups
Description: A global venture capital firm and accelerator with a strong presence in Latin America, investing in early-stage startups across various sectors. Focus: Broad, prioritizing tech and scalable business models. They have invested in over 170 LatAm companies. Program: A 16-week intensive program in Latin America with an initial $60,000 investment to eligible startups. Mentorship: Access to a global network of mentors and advisors. Location: Headquartered in Mexico for Latin American investments, but accepts startups from all over the region. Learn more about 500 Startups
2. Start-Up Chile
Description: A public accelerator program initiated by the Chilean government to stimulate business development. Focus: Open to high-potential entrepreneurs from any country looking to base their business in Chile, covering a wide range of industries. Program: Several programs including a pre-acceleration (4 months, $12k funding + $8k follow-on) and acceleration (4 months, $30k + potential follow-on $30k). Mentorship: Provides mentorship and access to a global network. Impact: Accelerated over 1,960 startups representing a $2.1 billion valuation. Learn more about Start-Up Chile
3. Google for Startups Accelerator
Description: Part of the global Google for Startups program, offering support for early-stage tech companies. Focus: Broad tech focus, with recent emphasis on AI, especially generative AI for social impact. Program: A 12-week equity-free accelerator program for Seed to Series A startups focusing on AI. Provides access to Google's products, people, and network. Mentorship: Dedicated mentoring from Google teams. Access to a network of Google and industry experts. Funding: Generative AI accelerator funding from $500K to $2M. Product credits and technical project support are available. Learn more about Google for Startups Accelerator
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4. Wayra
Description: The open innovation hub of Telefónica, seeking to connect startups with their extensive customer base. Focus: Technology-focused startups across various industries. Program: Offers acceleration programs with access to Telefónica's resources. Mentorship: Access to Telefónica's network, mentoring and expertise. Location: Multiple locations within South America including Brazil, Peru, and Venezuela. Explore Wayra
5. MassChallenge
Description: A global accelerator program focused on high-impact startups. Focus: Various industries but very selective (5% acceptance rate). Program: Does not invest directly but provides mentorship, resources, and networking opportunities. Zero cost and zero equity. Mentorship: Access to a global network of mentors and advisors. Impact: Accelerated 167 startups since 2016, raising a total of $132 million. Location: Based in Mexico for LatAm. Learn more about MassChallenge
6. Antler Brazil
Description: Identifies and invests in exceptional individuals to build tech startups. Focus: Early-stage tech startups. Program: Focused on identifying promising founders and building teams. Mentorship: Strong emphasis on mentorship and network. Location: Based in Brazil. Discover Antler Brazil
7. NXTP Labs
Description: A prominent accelerator with a focus on innovative technology startups. Focus: Startups working on cutting-edge technologies, clear vision, and strong team. Program: Provides mentorship, funding, and resources. Mentorship: Mentorship by industry experts and networking. Location: Argentina, Chile, Colombia, Mexico, and Uruguay. More about NXTP Labs
8. ACE Startups
Description: A Brazilian accelerator focused on supporting high-growth startups. Focus: Tech-based startups with high growth potential. Program: Tailored programs to help startups scale. Mentorship: Mentorship and networking opportunities. Location: Brazil. Learn more about ACE Startups
9. Startup Mexico
Description: The largest accelerator in Mexico, runs both incubator and accelerator programs. Focus: Various industries, supports early and growth-stage startups. Program: 6-month incubator and 10-month accelerator programs. Mentorship: Mentorship and networking support. Location: Mexico. Explore Startup Mexico
10. Founder Institute
Description: A global startup launch program that helps founders build enduring companies. Focus: Early-stage startups and aspiring entrepreneurs across industries. Program: Structured program with mentorship and support. Mentorship: Mentorship by a global network of successful entrepreneurs. Location: Multiple locations in Latin America. Learn more about Founder Institute
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11. The Yield Lab Latin America
Description: Focuses on agtech and food tech startups. Mentorship: Comprehensive mentorship and industry-driven networking. Discover The Yield Lab Latin America
12. BootUp360
Description: A global business incubation program with integrated mentorship. Focus: Varied industries focusing on scalable and innovative ideas. Mentorship: Comprehensive mentorship tailored for each startup. Explore BootUp360
13. Rockstart Colombia
Description: An accelerator focused on specific industries, based in Colombia. Focus: Varied industries with emphasis on innovative solutions. Mentorship: Industry-specific mentorship and resources. Location: Colombia. Learn more about Rockstart Colombia
14. Startup Farm
Description: Another notable accelerator program in Latin America. Focus: Varied tech industries with potential for high growth. Mentorship: Comprehensive mentoring and resource access. Explore Startup Farm
15. Baita Accelerator
Description: A Brazilian launch-stage startup accelerator. Focus: Early-stage startups with innovative solutions. Mentorship: Detailed mentorship and industry insights. Location: Brazil. Discover Baita Accelerator
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16. HubBog
Description: A renowned incubator focused on supporting tech startups in the early stages. Focus: Tech-focused startups in the development stage. Program: Mentorship, networking, and workspace for startups. Location: Colombia Website: Not provided.
17. SEED Accelerator
Description: Supports Brazilian tech startups focusing on early-stage development. Focus: Wide range of technology sectors. Program: Seed funding, mentorship, and co-working space. Location: Brazil. Website: Not provided.
18. Parallel18
Description: An accelerator that supports innovative Latin American startups aiming for global markets. Focus: Innovative solutions across varied sectors. Program: 20-week program with funding and mentorship. Location: Puerto Rico. Website: Not provided.
19. ChileGlobal Ventures
Description: A venture capital firm and accelerator helping startups grow exponentially. Focus: Varied industries with global potential. Program: Funding, mentorship, and market access. Location: Chile. Website: Not provided.
20. IN3 - Incubadora Instituto de Innovacion
Description: Incubates and accelerates startups with innovative technologies. Focus: Tech and innovative industry sectors. Program: Mentorship, resources, and investor access. Location: Paraguay. Website: Not provided.
21. Latam Startups
Description: Focuses on scaling Latin American startups in the global market. Focus: High growth potential startups across various sectors. Program: Incubation, acceleration, and market expansion support. Location: Canada (with a focus on LatAm startups). Website: Not provided.
22. Imagine Lab
Description: An innovation hub supporting tech startups in their early stages. Focus: Tech innovation and software-based solutions. Program: Funding, mentorship, and innovation resources. Location: Chile. Website: Not provided.
23. ARTech
Description: Supports early-stage startups with innovative art and technology solutions. Focus: Intersection of art, design, and technology. Program: Funding and mentorship focusing on artistic tech startups. Location: Uruguay. Website: Not provided.
24. Techno Latina
Description: An incubator focusing on women-led tech startups. Focus: Empowering female entrepreneurs in tech sectors. Program: Comprehensive mentorship and resources. Location: Latin America. Website: Not provided.
25. BioCubaFarma
Description: An incubation program supporting biotech and pharmatech startups. Focus: Biotechnology and pharmaceutical innovation. Program: Funding, lab resources, and mentorship. Location: Cuba. Website: Not provided.
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FAQ
Q: What is a top incubator for AI startups in South America?
A: 500 Startups is known for its strong presence in Latin America and its investment in early-stage tech startups. Read more about 500 Startups.
Q: Which incubator is supported by the Chilean government?
A: Start-Up Chile is a public accelerator program focused on stimulating business development in Chile. Learn more about Start-Up Chile.
Q: What program does Google offer for AI startups?
A: Google for Startups Accelerator offers a 12-week equity-free program for Seed to Series A AI startups. Discover Google for Startups Accelerator.
Q: Which accelerator is affiliated with Telefónica?
A: Wayra is the open innovation hub of Telefónica, providing access to resources and mentorship. Explore Wayra.
Q: Which accelerator in Latin America has a 5% acceptance rate?
A: Mass Challenge is a highly selective global accelerator with a 5% acceptance rate. Read more about Mass Challenge.
Q: What is Antler Brazil known for?
A: Antler Brazil focuses on identifying and investing in exceptional individuals to build tech startups.
Q: Which accelerator has multiple locations in South America?
A: NXTP Labs operates in Argentina, Chile, Colombia, Mexico, and Uruguay, focusing on innovative technology startups. Learn more about NXTP Labs.
Q: Which Brazilian accelerator supports high-growth tech startups?
A: ACE Startups is a Brazilian accelerator providing tailored programs for high-growth tech startups. Read more about ACE Startups.
Q: What is the largest accelerator in Mexico?
A: Startup Mexico is known as the largest accelerator in Mexico, supporting startups through both incubator and accelerator programs. Explore Startup Mexico.
Q: Which global program helps founders build enduring companies?
A: Founder Institute provides a structured program with mentorship for early-stage startups across various industries. Learn more about Founder Institute.
About the Author
Violetta Bonenkamp, also known as MeanCEO, is an experienced startup founder with an impressive educational background including an MBA and four other higher education degrees. She has over 20 years of work experience across multiple countries, including 5 years as a solopreneur and serial entrepreneur.
Violetta is a true multiple specialist who has built expertise in Linguistics, Education, Business Management, Blockchain, Entrepreneurship, Intellectual Property, Game Design, AI, SEO, Digital Marketing, cyber security and zero code automations. Her extensive educational journey includes a Master of Arts in Linguistics and Education, an Advanced Master in Linguistics from Belgium (2006-2007), an MBA from Blekinge Institute of Technology in Sweden (2006-2008), and an Erasmus Mundus joint program European Master of Higher Education from universities in Norway, Finland, and Portugal (2009).
She is the founder of Fe/male Switch, a startup game that encourages women to enter STEM fields, and also leads CADChain, and multiple other projects like the Directory of 1,000 Startup Cities with a proprietary MeanCEO Index that ranks cities for female entrepreneurs. Violetta created the "gamepreneurship" methodology, which forms the scientific basis of her startup game. She also builds a lot of SEO tools for startups. Her achievements include being named one of the top 100 women in Europe by EU Startups in 2022 and being nominated for Impact Person of the year at the Dutch Blockchain Week. She is an author with Sifted and a speaker at different Universities. Recently she published a book on Startup Idea Validation the right way: from zero to first customers and beyond and launched a Directory of 1,500+ websites for startups to list themselves in order to gain traction and build backlinks.