Top 25 VCs for Deeptech Startups in South America in 2025: A Comprehensive Guide
The deeptech startup ecosystem in South America is witnessing significant growth with startups driving cutting-edge innovations in fields such as AI, biotech, and clean energy. Venture capital firms are playing a pivotal role in supporting these startups by providing not just funding but also expert guidance and a robust network. Here is a curated list of the Top 25 VCs for Deeptech Startups in South America in 2025, complete with details on their focus areas, portfolio, stages they invest in, and links to their official websites.
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1. Kaszek Ventures
Focus: High-impact tech companies in Latin America, including SaaS and potentially deep tech.
Track Record: Invested in 58 companies across seven countries.
Support: Offers guidance on strategy, operations, growth, HR, and networking.
Stage: Primarily invests in Seed-stage startups.
Region: Active across Latin America.
2. Bossanova Investimentos
Focus: Pre-seed and seed stage B2B or B2B2C companies with scalable digital business models.
Activity: Claims to be the most active VC in Latin America.
Investment Size: Typically invests between BRL 100k and BRL 500k.
Requirement: Companies must have at least BRL 20k in monthly income.
Location: São Paulo, Brazil.
3. Canary
Focus: Exclusively on LatAm startups, including digital health and real estate platforms.
Region: Focuses on Latin American startups.
Stage: Invests in companies across various stages.
Portfolio: Backed companies like digital health specialist Alice and Loft (real estate platform).
Activity: One of the most active investors in Latin America.
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4. Monashees
Focus: Partners with founders revolutionizing large markets.
Approach: Human-values-first approach, supporting founders from early stages.
Region: Pioneer venture capital firm in Latin America.
Stage: Supports entrepreneurs starting from their very first movements through expansion funds.
Activity: One of the most active VCs in LatAm.
5. NXTP Labs
Focus: Early-stage tech companies in Latin America, with a specialization in Fintech and Agtech since 2015.
Network: Offers a powerful network for entrepreneurs, investors, and executives.
Region: Active across Latin America.
Stage: Seed, Series A, Series B.
Size of Fund: $103M.
6. Manutara Ventures
Focus: Early-stage tech ventures with a global mindset.
Region: Leading VC fund in Chile and Latin America.
Network: Part of the global Draper Network since 2018.
Stage: Early Stage.
Goal: Aims to provide exceptional entrepreneurs with key resources to scale their businesses.
7. Astella Investimentos
Focus: Promising tech companies in Brazil, helping develop the startup ecosystem.
Support: Mentors provide guidance in areas like customer acquisition, product development, and company training.
Location: Based in São Paulo, Brazil.
Goal: Focus on entrepreneurs and their journey, supporting scalability and business development.
Stage: Focuses on early stages (Seed, Series A).
8. GRIDX Exponential
Focus: Deep tech startups.
Region: Based in Argentina.
Role: Plays a key role in finding promising research that can be turned into a high-tech startup.
Goal: Accelerates technology transfer so new solutions find their customers.
9. Zentynel
Focus: Deep tech startups.
Region: Based in Chile.
Role: Plays a key role in finding promising research that can be turned into a high-tech startup.
Goal: Accelerates technology transfer so new solutions find their customers.
10. Vesper Ventures
Focus: Deep tech startups.
Region: Based in Brazil.
Role: Plays a key role in finding promising research that can be turned into a high-tech startup.
Goal: Accelerates technology transfer so new solutions find their customers.
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11. A.B.Seed Ventures
Focus: B2B SaaS investments.
Stage: Seed stage companies.
Support: Provides business with the basics for fast growth.
Region: Invests in Brazil.
12. FJ Labs
Focus: Startups across all stages and geographies.
Activity: One of the most active investors in Latin America.
Region: Global investor with activity in LatAm.
Portfolio: Investments include Instacarro and Kitchenita.
Stage: All stages.
13. DOMO.VC
Focus: Active in Latin America.
Region: São Paulo based.
14. Latitud
Focus: Active in Latin America.
Region: São Paulo based.
15. Norte Ventures
Focus: Active in Latin America.
Region: São Paulo based.
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16. Magma Partners
Focus: Active in Latin America.
Region: Santiago, Chile based.
17. Valor Capital
Focus: Active in Latin America.
Region: New York based.
18. MAYA Capital
Focus: Early-stage fund supporting leaders catalyzing change in Latin America.
Support: Provides smart capital and advisory.
19. Vine Ventures
Focus: Early-stage, software-focused, investing in the US, Latin America, and Israel.
Mandate: Helps companies navigate challenges building generational businesses.
Stage: Pre-Seed, Seed, Series A, Series B+.
Region: Focuses on the U.S., Latin America, and Israel.
20. Quona Capital
Focus: Fintech companies in emerging markets.
Track Record: 47 active portfolio companies, raised a total of $4B in equity.
21. Zenda
Focus: B2B tech in the U.S. and LATAM, with a thesis-driven approach.
Stage: Pre-Seed, Seed,
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FAQ
Q: Which VC is most active in Latin America?
A: Bossanova Investimentos claims to be the most active VC in Latin America. Learn more about Bossanova Investimentos.
Q: Which VC focuses on high-impact tech companies in Latin America?
A: Kaszek Ventures focuses on high-impact tech companies in Latin America. Learn more about Kaszek Ventures.
Q: Which VC has a specialization in Fintech and Agtech?
A: NXTP Labs has a specialization in Fintech and Agtech. Learn more about NXTP Labs.
Q: Which VC is a leading fund in Chile and Latin America?
A: Manutara Ventures is a leading VC fund in Chile and Latin America. Learn more about Manutara Ventures.
Q: Which VC focuses exclusively on LatAm startups including digital health and real estate platforms?
A: Canary focuses exclusively on LatAm startups including digital health and real estate platforms. Learn more about Canary.
Q: Which VC firm is based in Argentina and plays a key role in deep tech startups?
A: GRIDX Exponential is based in Argentina and focuses on deep tech startups. Learn more about GRIDX Exponential.
Q: Which VC based in Chile focuses on deep tech startups?
A: Zentynel is based in Chile and focuses on deep tech startups. Learn more about Zentynel.
Q: Which deep tech-focused VC is based in Brazil?
A: Vesper Ventures is based in Brazil and focuses on deep tech startups. Learn more about Vesper Ventures.
Q: Which VC firm invests in B2B SaaS in Brazil?
A: A.B.Seed Ventures invests in B2B SaaS in Brazil. Learn more about A.B.Seed Ventures.
Q: Which is one of the most active global investors in Latin America?
A: FJ Labs is one of the most active global investors in Latin America. Learn more about FJ Labs.
About the Author
Violetta Bonenkamp, also known as MeanCEO, is an experienced startup founder with an impressive educational background including an MBA and four other higher education degrees. She has over 20 years of work experience across multiple countries, including 5 years as a solopreneur and serial entrepreneur.
Violetta is a true multiple specialist who has built expertise in Linguistics, Education, Business Management, Blockchain, Entrepreneurship, Intellectual Property, Game Design, AI, SEO, Digital Marketing, cyber security and zero code automations. Her extensive educational journey includes a Master of Arts in Linguistics and Education, an Advanced Master in Linguistics from Belgium (2006-2007), an MBA from Blekinge Institute of Technology in Sweden (2006-2008), and an Erasmus Mundus joint program European Master of Higher Education from universities in Norway, Finland, and Portugal (2009).
She is the founder of Fe/male Switch, a startup game that encourages women to enter STEM fields, and also leads CADChain, and multiple other projects like the Directory of 1,000 Startup Cities with a proprietary MeanCEO Index that ranks cities for female entrepreneurs. Violetta created the "gamepreneurship" methodology, which forms the scientific basis of her startup game. She also builds a lot of SEO tools for startups. Her achievements include being named one of the top 100 women in Europe by EU Startups in 2022 and being nominated for Impact Person of the year at the Dutch Blockchain Week. She is an author with Sifted and a speaker at different Universities. Recently she published a book on Startup Idea Validation the right way: from zero to first customers and beyond and launched a Directory of 1,500+ websites for startups to list themselves in order to gain traction and build backlinks.
