Top 25 Cities for Deeptech Startups in South America in 2025
The future of deeptech in South America is looking bright, with several cities emerging as hubs for innovation and technology. As we step into 2025, here is a detailed look at the Top 25 Cities for Deeptech Startups in South America, based on the latest trends and data.
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1. São Paulo, Brazil
Tech Ecosystem: Recognized as the largest and most dynamic tech hub in Brazil and one of the top tech cities in Latin America.
Startup Activity: Accounts for nearly 60% of Brazil’s tech startups. Home to numerous unicorn companies such as Nubank and iFood.
Talent Pool: Largest tech talent pool in Latin America, with over 1.5 million IT professionals.
Investment: Led the region with $6.8 billion in venture capital investment in 2021.
Key Sectors: Fintech, E-commerce, Healthtech, Agritech, Software Development, AI, and Blockchain.
2. Buenos Aires, Argentina
Tech Ecosystem: A major tech hub in South America, known for its vibrant startup ecosystem.
Talent Pool: Strong STEM-focused educational system, leading to a large talent pool of software developers and engineers.
Startup Activity: Dynamic startup hotspot, with a large concentration of deep tech startups.
Investment: Argentina has the most deeptech companies in South America (103), with a collective value of $1.9 billion.
Key Sectors: Biotech, Spacetech, Software Development.
3. Mexico City, Mexico
Tech Ecosystem: Heart of Mexico's tech scene, often referred to as the “Silicon Valley of Latin America.”
Startup Activity: Bustling hub for startups and tech giants.
Talent Pool: Substantial talent pool of software developers.
Investment: Attracts significant investment in the region.
Key Sectors: Fintech, E-commerce, Software Development.
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4. Bogotá, Colombia
Tech Ecosystem: One of the fastest-growing tech hubs in Latin America.
Startup Activity: Rapid increase in tech startups due to government initiatives.
Talent Pool: More than 84,000 tech professionals.
Growth: Tech sector grew by 21% in 2021.
Key Sectors: Software Development and IT Services
5. Santiago, Chile
Tech Ecosystem: A significant player in Latin American tech, focusing on Cloud and IoT, as well as clean energy.
Startup Activity: Vibrant startup scene, attracting international tech companies.
Investment: A key destination for investment in Latin America.
Key Sectors: Fintech, Cloud Computing, IoT, Clean Energy.
Foreign Tech Presence: Home to hubs of major corporations such as Amazon, Microsoft, Google, and Oracle.
6. Guadalajara, Mexico
Tech Ecosystem: Known as “Mexico's Silicon Valley”.
Key Sectors: Technology and Innovation
Talent Pool: Skilled Talent in AI
7. Monterrey, Mexico
Tech Ecosystem: Known for its industrial prowess and growing tech sector.
Startup Activity: Serves as a hub for startups and tech companies.
Key Sectors: Industrial Tech and Software Development
8. Medellín, Colombia
Tech Ecosystem: Growing tech hub with a rising startup scene.
Talent Pool: A promising pool of software developers and IT professionals.
Key Sectors: Software Development and IT services.
9. Montevideo, Uruguay
Tech Ecosystem: Reputation as a hub for software development.
Internet Access: High internet access rate with fast download speeds.
Startup Activity: Growing Fintech ecosystem.
Key Sectors: Fintech and Software Development
10. Curitiba, Brazil
Tech Ecosystem: Known for its sustainability and urban planning innovations.
Key Sectors: Sustainable tech innovations, software development.
Talent Pool: Part of Brazil's large talent pool of tech professionals.
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11. Lima, Peru
Tech Ecosystem: Emerging as a growing tech hub in Latin America.
Key Sectors: Fintech, E-commerce
Investment: Increasing venture capital interest.
12. Quito, Ecuador
Tech Ecosystem: Developing tech ecosystem with government support.
Key Sectors: Software development, IoT
Talent Pool: Growing number of engineers and IT professionals.
13. La Paz, Bolivia
Tech Ecosystem: Growing innovation ecosystem with startups in fintech and health tech.
Key Sectors: Fintech, Healthtech
Government Support: Strong government initiatives to support startups.
14. Caracas, Venezuela
Tech Ecosystem: Developing tech sector despite economic challenges.
Key Sectors: Fintech, E-commerce
Talent Pool: A growing number of skilled tech professionals.
15. Asunción, Paraguay
Tech Ecosystem: Emerging tech city with a growing number of startups.
Key Sectors: Fintech, Agtech
Government Support: Local initiatives promoting entrepreneurship.
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16. Recife, Brazil
Tech Ecosystem: Known for its innovation hubs and research centers.
Key Sectors: Software development, AI
Investment: Attracting increasing amounts of venture capital.
17. Fortaleza, Brazil
Tech Ecosystem: Growing hub for startups focusing on deep tech innovations.
Key Sectors: Software development, AI, Healthtech
Government Support: Strong local government support for tech initiatives.
18. Porto Alegre, Brazil
Tech Ecosystem: Known for its tech parks and innovation districts.
Key Sectors: Software development, healthtech
Investment: Attracting a significant amount of venture capital.
19. Brasília, Brazil
Tech Ecosystem: The capital city is leveraging its educational institutions for tech growth.
Key Sectors: Government tech, AI, software development
Government Support: Strong governmental support for tech innovation.
20. Córdoba, Argentina
Tech Ecosystem: Known for its innovative startups and entrepreneurial culture.
Key Sectors: Software development, e-commerce.
Investment: A growing hub for venture capital.
21. Valparaíso, Chile
Tech Ecosystem: Developing tech city with a focus on marine tech and renewable energy.
Key Sectors: Marine tech, renewable energy development.
Government Support: Local government initiatives to support tech startups.
22. Rosario, Argentina
Tech Ecosystem: Emerging tech hub with a focus on agritech.
Key Sectors: Agtech, software development
Investment: Attracting venture capital interest.
23. Belo Horizonte, Brazil
Tech Ecosystem: Known for its research and development centers.
Key Sectors: Healthtech, software development
Investment: Increasing investment in health tech.
24. Tijuana, Mexico
Tech Ecosystem: Rapidly growing as a tech hub with strong bi-national startups.
Key Sectors: Healthtech, software development
25. Cartagena, Colombia
Tech Ecosystem: Emerging tech city with strong government support for innovation.
Key Sectors: Fintech, software development
Government Support: Promoting innovation through public-private partnerships.
This list reflects the significant progress and potential across various cities in South America. The region is poised for substantial growth in the deep tech sector, underpinned by strong government support, a skilled talent pool, and increasing venture capital investment.
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FAQ
Q: Which city is the leading hub for deep tech startups in South America in 2025?
A: São Paulo, Brazil is recognized as the largest and most dynamic tech hub in South America, often called the "beating heart of Latin American tech". Learn more about São Paulo’s tech scene.
Q: What city in Argentina is prominent for deep tech startups?
A: Buenos Aires, Argentina is a major tech hub known for its vibrant startup ecosystem and innovative mindset, making it a key player in Latin America's tech industry. Explore Buenos Aires’ startup ecosystem.
Q: Which Mexican city is referred to as the “Silicon Valley of Latin America”?
A: Mexico City is often referred to as the “Silicon Valley of Latin America” due to its strong ecosystem of startups and tech giants.
Q: What tech sectors are prominent in Bogotá, Colombia?
A: In Bogotá, the key sectors for tech startups are Software Development and IT Services.
Q: What are the key technology sectors in Santiago, Chile?
A: Santiago focuses on Fintech, Cloud Computing, IoT, and Clean Energy.
Q: Which city is considered “Mexico's Silicon Valley”?
A: Guadalajara, Mexico is often called "Mexico's Silicon Valley" for its significant role in technology and innovation.
Q: What kind of tech scene is Monterrey, Mexico known for?
A: Monterrey is known for its industrial tech and growing software development sector. Learn more about Monterrey’s role in tech.
Q: What sectors is Montevideo, Uruguay's tech ecosystem strong in?
A: Montevideo has a strong reputation in Fintech and Software Development, along with high internet access rates. Discover Montevideo’s fintech ecosystem.
Q: Which city in Brazil is known for its sustainable tech innovations?
A: Curitiba, Brazil is renowned for its sustainability and urban planning innovations, as well as its contributions to software development.
Q: What is the key characteristic of Medellín, Colombia’s tech scene?
A: Medellín has a growing tech hub with a rising startup scene and a promising pool of software developers. Explore Medellín’s tech sector.
About the Author
Violetta Bonenkamp, also known as MeanCEO, is an experienced startup founder with an impressive educational background including an MBA and four other higher education degrees. She has over 20 years of work experience across multiple countries, including 5 years as a solopreneur and serial entrepreneur.
Violetta is a true multiple specialist who has built expertise in Linguistics, Education, Business Management, Blockchain, Entrepreneurship, Intellectual Property, Game Design, AI, SEO, Digital Marketing, cyber security and zero code automations. Her extensive educational journey includes a Master of Arts in Linguistics and Education, an Advanced Master in Linguistics from Belgium (2006-2007), an MBA from Blekinge Institute of Technology in Sweden (2006-2008), and an Erasmus Mundus joint program European Master of Higher Education from universities in Norway, Finland, and Portugal (2009).
She is the founder of Fe/male Switch, a startup game that encourages women to enter STEM fields, and also leads CADChain, and multiple other projects like the Directory of 1,000 Startup Cities with a proprietary MeanCEO Index that ranks cities for female entrepreneurs. Violetta created the "gamepreneurship" methodology, which forms the scientific basis of her startup game. She also builds a lot of SEO tools for startups. Her achievements include being named one of the top 100 women in Europe by EU Startups in 2022 and being nominated for Impact Person of the year at the Dutch Blockchain Week. She is an author with Sifted and a speaker at different Universities. Recently she published a book on Startup Idea Validation the right way: from zero to first customers and beyond and launched a Directory of 1,500+ websites for startups to list themselves in order to gain traction and build backlinks.
