Top 20 Incubators for Deeptech Startups in North America in 2025
The deeptech landscape is evolving rapidly, with incubators playing a crucial role in nurturing innovation and facilitating growth. These programs offer invaluable resources, mentorship, funding, and networking opportunities to startups working with advanced technologies rooted in scientific and engineering principles. Here’s a comprehensive list of the Top 20 Incubators for Deeptech Startups in North America in 2025, complete with details on locations, investments, program durations, and links to their official websites.
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1. Y Combinator (YC)
Location: Mountain View, California
Investment: $500,000 ($125,000 for 7% equity + $375,000 uncapped SAFE)
Program Duration: 3 months
Focus: Open to all industries, strong emphasis on tech startups including deep tech.
Key Data Points:
- Notable alumni include Airbnb, Dropbox, and Reddit.
- Provides intense mentorship and Demo Day exposure to top investors.
- Extensive and prestigious alumni network.
- Apply to Y Combinator
2. Techstars
Location: Global (50+ programs worldwide, many in North America)
Investment: Typically $120,000 for 6% equity
Program Duration: 3 months
Focus: Diverse industries, including health tech, fintech, and some deep tech focused programs.
Key Data Points:
- Hands-on mentorship and access to a global network of investors.
- Offers perks valued at over $4 million; has supported over 9000 founders.
- Strong track record with alumni like SendGrid and ClassPass.
- Techstars Application
3. MARL 5G Accelerator
Location: Fremont, California
Investment: $50,000 (amount may vary)
Program Duration: Not specified
Focus: DeepTech products and services.
Key Data Points:
- Specifically focused on DeepTech.
- Access to mentors and resources as part of a larger tech ecosystem.
- MARL 5G Accelerator
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4. Greentown Labs
Location: Somerville, Massachusetts
Investment: Not specified
Program Duration: Not specified
Focus: Clean technology startups, including renewable energy and sustainability.
Key Data Points:
- Largest clean technology startup incubator in North America.
- Provides access to lab facilities and equipment.
- Dedicated community fostering positive environmental impact.
- Greentown Labs
5. Entrepreneurs Roundtable Accelerator (ERA)
Location: New York, New York
Investment: $150,000 for 6% equity
Program Duration: 4 months
Focus: Technology startups across all major industries.
Key Data Points:
- Offers a mentor network of over 500 experts and free office space in Manhattan.
- Provides additional benefits from partners like Microsoft and AWS.
- Funded 275 startups with a high exit rate of 91.
- ERA
6. Polsky Deep Tech Ventures (University of Chicago)
Location: Chicago, Illinois
Investment: Not specified
Program Duration: Full Spectrum
Focus: Translating innovations into startups with a deep scientific or technological basis.
Key Data Points:
- Full spectrum accelerator and support initiative based at the University of Chicago Polsky Center.
- Dedicated to advancing deep tech innovations.
- Polsky Deep Tech Ventures
7. Alchemist Accelerator
Location: Silicon Valley, San Francisco, and other locations
Investment: Typically $36,000 for 5% equity.
Program Duration: Not specified
Focus: Exclusively for founders whose revenue comes from enterprises.
Key Data Points:
- Focuses on enterprise-scale startups with robust mentorship and scaling resources.
- Strong network connections to Silicon Valley's business ecosystem.
- Alchemist Accelerator
8. Future Labs
Location: New York, New York
Investment: Not specified
Program Duration: Not specified
Focus: Healthcare and AI
Key Data Points:
- Designed with a focus on AI and health tech solutions.
- Experienced in helping deep tech companies grow successfully.
- Future Labs
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9. MassChallenge
Location: Global (Boston, Switzerland, Israel, etc.)
Investment: Not specified
Program Duration: Not specified
Focus: High-potential startups focused on solving large-scale challenges.
Key Data Points:
- Offers a solid global network for startup support.
- Operates with zero equity taken from participants.
- Emphasis on developing high-impact solutions for real-world problems.
- MassChallenge
10. The Yield Lab North America
Location: St. Louis, Missouri
Investment: $100,000 (amount may vary)
Program Duration: Not specified
Focus: Revolutionizing agrifood systems through sustainable entrepreneurship.
Key Data Points:
- Focused at the intersection of technology and agriculture, supporting agrifood entrepreneurs.
- The Yield Lab
11. StartX
Location: Stanford, California
Investment: Not specified
Program Duration: Not specified
Focus: Companies leveraging technology with a focus on deep science.
Key Data Points:
- Operates under Stanford University’s ecosystem.
- Provides mentorship from top-tier entrepreneurs and educators.
12. Hardware Club
Location: Global (with strong presence in North America)
Investment: Not specified
Program Duration: Not specified
Focus: Hardware startups and product development.
Key Data Points:
- Industry-focused network aimed at hardware entrepreneurs.
- Offers prototyping, materials sourcing, and funding assistance.
13. RocketSpace
Location: San Francisco, California
Investment: Not specified
Program Duration: Not specified
Focus: Tech startups including deeptech innovations.
Key Data Points:
- Tailored for scaling tech companies with access to industry-specific resources.
- Provides unique networking opportunities with major tech players.
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14. Capital Innovators
Location: St. Louis, Missouri
Investment: $100,000 for 6% equity
Program Duration: 12 weeks
Focus: Tech startups across various sectors, including deeptech.
Key Data Points:
- Focus on providing support and mentorship for early-stage startups.
- Access to local investors and resources.
15. Village Capital
Location: D.C. and globally
Investment: Not specified
Program Duration: Varies
Focus: Health, financial, and educational tech focusing on social impact.
Key Data Points:
- Unique model where startups evaluate each other’s progress.
- Offers a curriculum-based approach for connecting with investors.
16. SBC (Startupbootcamp)
Location: Global (with programs in North America)
Investment: Typically $15,000 for 6% equity
Program Duration: 3 months
Focus: Specific industry verticles including deep tech and fintech.
Key Data Points:
- Acceleration programs in multiple cities to foster innovation.
- Offers mentorship, office space, and access to a global networking platform.
17. The Founder Institute
Location: Global (offices in North America)
Investment: Not specified
Program Duration: 14 weeks
Focus: Early-stage founders across all industries, including deeptech.
Key Data Points:
- Focused on developing the skills and network needed to succeed.
- Offers a robust, structured program for aspiring entrepreneurs.
18. Dreamit Ventures
Location: Philadelphia, Pennsylvania and New York, New York
Investment: Not specified
Program Duration: 14 weeks
Focus: Health tech, secure tech, and urban tech startups.
Key Data Points:
- Provides extensive connections to investors and industry leaders.
- Well-structured program to help startups scale and innovate in their sectors.
19. Plug and Play Tech Center
Location: Sunnyvale, California
Investment: Varies by startup
Program Duration: Year-round program with vertical-specific tracks
Focus: Wide range, including deep tech, insurtech, and fintech.
Key Data Points:
- Access to a diverse network of industry leaders and global investors.
- Offers pilot programs and extensive mentoring.
20. Tactical Tech
Location: San Francisco, California
Investment: Not specified
Program Duration: Not specified
Focus: Technology that drives social transformation, tech for good.
Key Data Points:
- Supports startups that create impact through technology.
- Engages with an overarching mission for sustainability and equity.
This list provides an insightful starting point for founders seeking top incubators that cater to deeptech startups in North America for 2025. Each incubator offers a unique blend of resources and opportunities, tailored to support innovation in various technology-driven fields.
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FAQ
Q: What is a well-known incubator for deep tech startups?
A: Y Combinator (YC) is one of the most prestigious accelerators globally, known for its intensive mentorship and strong focus on tech startups, including deep tech. Learn more about Y Combinator.
Q: Which incubator has a specific focus on clean technology?
A: Greentown Labs in Somerville, Massachusetts, is recognized as the largest clean technology startup incubator in North America, providing specialized equipment and lab facilities. Discover Greentown Labs.
Q: Which program supports the intersection of technology and agriculture?
A: The Yield Lab North America focuses on revolutionizing agrifood systems through sustainable entrepreneurship and provides funding and resources to entrepreneurs in this sector. Learn more about The Yield Lab.
Q: What support does Techstars offer to startups?
A: Techstars provides hands-on mentorship, access to a global network of investors, and numerous perks valued at over $4 million to the startups it supports. Check out Techstars.
Q: Who can participate in the Polsky Deep Tech Ventures program?
A: The Polsky Deep Tech Ventures program, based at the University of Chicago, supports startups that translate innovations with a deep science or technology basis into viable business models. Explore Polsky Deep Tech Ventures.
Q: What is the funding offered by the Entrepreneurs Roundtable Accelerator (ERA)?
A: The Entrepreneurs Roundtable Accelerator (ERA) offers $150,000 in exchange for 6% equity and provides a robust mentor network of over 500 experts. Learn more about ERA.
Q: Which incubator specializes in healthcare and AI?
A: Future Labs in New York focuses on healthcare and AI, helping deep tech companies in those sectors grow and succeed. Check out Future Labs.
Q: What does MassChallenge do for startups?
A: MassChallenge supports high-potential startups across various industries, focusing on solving large-scale challenges and operates with zero equity taken from participants. Explore MassChallenge.
Q: Where is the Alchemist Accelerator located, and what does it focus on?
A: Alchemist Accelerator, located in Silicon Valley, focuses on enterprise startups and provides mentorship and resources to businesses whose revenue comes from enterprises. Discover Alchemist Accelerator.
About the Author
Violetta Bonenkamp, also known as MeanCEO, is an experienced startup founder with an impressive educational background including an MBA and four other higher education degrees. She has over 20 years of work experience across multiple countries, including 5 years as a solopreneur and serial entrepreneur.
Violetta is a true multiple specialist who has built expertise in Linguistics, Education, Business Management, Blockchain, Entrepreneurship, Intellectual Property, Game Design, AI, SEO, Digital Marketing, cyber security and zero code automations. Her extensive educational journey includes a Master of Arts in Linguistics and Education, an Advanced Master in Linguistics from Belgium (2006-2007), an MBA from Blekinge Institute of Technology in Sweden (2006-2008), and an Erasmus Mundus joint program European Master of Higher Education from universities in Norway, Finland, and Portugal (2009).
She is the founder of Fe/male Switch, a startup game that encourages women to enter STEM fields, and also leads CADChain, and multiple other projects like the Directory of 1,000 Startup Cities with a proprietary MeanCEO Index that ranks cities for female entrepreneurs. Violetta created the "gamepreneurship" methodology, which forms the scientific basis of her startup game. She also builds a lot of SEO tools for startups. Her achievements include being named one of the top 100 women in Europe by EU Startups in 2022 and being nominated for Impact Person of the year at the Dutch Blockchain Week. She is an author with Sifted and a speaker at different Universities. Recently she published a book on Startup Idea Validation the right way: from zero to first customers and beyond and launched a Directory of 1,500+ websites for startups to list themselves in order to gain traction and build backlinks.
