Top 15 Angel Investors for AI Startups in North America in 2025
The year 2025 marks a pivotal moment for AI-driven innovation in North America, with a burgeoning network of investors who are keen to support the next generation of AI startups. This article outlines the Top 15 Angel Investors for AI Startups in North America, highlighting their investment focus, notable contributions, and strategies for fostering innovation in this dynamic sector.
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1. Andreessen Horowitz (a16z)
Investment Stage: Seed to Growth
Notable AI Investments: OpenAI, Databricks, Shield AI
Assets Under Management: ~$42 Billion
Focus: Visionary entrepreneurs and innovative technologies, particularly in AI.
Approach: Hands-on support with a long-term and optimistic investment strategy.
2. Sequoia Capital
Investment Stage: Seed to Growth
Notable AI Investments: DeepMind, Iconic.AI, Fireworks AI
Founded: 1972
Portfolio: Google, Airbnb, Stripe, WhatsApp
Approach: Offers strategic guidance from inception through IPO.
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3. Greylock Partners
Investment Stage: Early Stage
Notable AI Investments: Adept AI, Atomic AI, Seven AI
Founded: 1965
Portfolio: LinkedIn, Facebook, Airbnb
Focus: Targeting early-stage tech companies with disruptive potential.
4. Data Collective (DCVC)
Focus: Deep tech investments, focusing on AI and machine learning.
Founded: 2011
Portfolio: Companies across healthcare, agriculture, and cybersecurity sectors.
Approach: A commitment to deep tech innovation, offering both financial and strategic guidance.
5. Wei Guo
Role: Managing Partner at UpHonest Capital and founder of Wei Capital
Expertise: Cross-sector early-stage investments, especially in AI and digital firms.
Track Record: Over 70 portfolio firms with valuations exceeding $100 million USD.
Awards: Recognized in Forbes 30 Under 30 and named a top angel investor in AI by VentureBeat (2017).
Focus: Consumer technology, fintech, and AI.
6. Khosla Ventures
Focus: High-impact innovations, particularly in AI.
Approach: Seeks ventures aiming to disrupt conventional practices and open billion-dollar market opportunities.
Recent Investment: LotiAI, specializing in likeness protection technology.
7. 7BC Venture Capital
Focus: Pioneering advancements in AI technology through strategic investments.
Notable For: Their focus on AI-driven startup ventures.
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8. Flying Fish Partners
Focus: Specializing in AI investments and funding groundbreaking startups.
Notable For: Investing in innovative companies that disrupt industries with AI.
9. Will Griffith
Role: Founding Partner at ICONIQ Growth
Investment Stage Focus: Early, Mid, and Late Stage
Stage Breakdown: Early stage (17), mid stage (54), late stage (44).
10. Edward Lando
Role: Investor
Stage Breakdown: Early stage (103), mid stage (16), late stage (5).
11. AI Fund
Focus: Investing in AI-first companies that leverage advanced machine learning technologies.
Notable For: Rapid growth in tech ecosystems, primarily within AI verticals.
12. Union Square Ventures
Focus: Investing across various sectors with a keen interest in AI and data.
Notable For: Strong portfolio of tech-driven companies with AI capabilities.
13. DataX Ventures
Focus: AI and big-data startups transforming traditional industries.
Approach: Provides strategic advice alongside capital investment.
14. Bessemer Venture Partners
Focus: Investing in early-stage technology companies, particularly AI startups.
Notable For: A diverse portfolio across various AI applications and technologies.
15. Lerer Hippeau
Focus: Seed and early-stage investments in tech, including AI-driven solutions.
Notable For: A diverse portfolio that includes AI startups tackling real-world problems.
This detailed list showcases the significant players in the angel investing landscape for AI startups across North America as we progress in 2025, featuring their investment strategies, notable contributions, and overarching focuses.
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FAQ
Q: Who are some notable investors for AI startups in North America in 2025?
A: Notable investors include Andreessen Horowitz (a16z), Sequoia Capital, and Greylock Partners. Learn more about these investors.
Q: What type of investment stage do these investors typically focus on?
A: Many of these investors focus on a range of stages from seed to growth, with some specializing in early-stage investments. Discover more about their investment stages.
Q: What are some notable AI startups that these investors have backed?
A: Some notable AI startups include OpenAI, DeepMind, and Shield AI. Learn about these investments.
Q: Who is Wei Guo and what is his focus in investments?
A: Wei Guo is the Managing Partner at UpHonest Capital, focusing on early-stage investments in consumer technology, fintech, and AI. His portfolio includes firms achieving valuations over $100 million USD. Read more about Wei Guo.
Q: What strategic approach does Khosla Ventures take?
A: Khosla Ventures seeks high-impact innovations, focusing on ventures that challenge conventional norms and targeting large markets or billion-dollar opportunities. Find out more.
Q: How does Data Collective (DCVC) position its investments?
A: Data Collective (DCVC) is committed to deep tech investments, particularly in AI and machine learning, providing both financial and strategic guidance to its portfolio companies. Learn more about their approach.
Q: What focus does 7BC Venture Capital have in its investments?
A: 7BC Venture Capital focuses on driving advancements in AI technology through strategic investments, particularly in innovative startups. Read more about 7BC Venture Capital.
Q: Who is Will Griffith and what is his investment focus?
A: Will Griffith is a Founding Partner at ICONIQ Growth, focusing on early, mid, and late-stage investments. His diverse portfolio includes a significant number of companies at different growth stages. Discover more about Will Griffith.
Q: What is the investment stage focus for Edward Lando?
A: Edward Lando focuses on early, mid, and late-stage investments, with a substantial number of early-stage deals in his portfolio. Learn more about Edward Lando.
About the Author
Violetta Bonenkamp, also known as MeanCEO, is an experienced startup founder with an impressive educational background including an MBA and four other higher education degrees. She has over 20 years of work experience across multiple countries, including 5 years as a solopreneur and serial entrepreneur.
Violetta is a true multiple specialist who has built expertise in Linguistics, Education, Business Management, Blockchain, Entrepreneurship, Intellectual Property, Game Design, AI, SEO, Digital Marketing, cyber security and zero code automations. Her extensive educational journey includes a Master of Arts in Linguistics and Education, an Advanced Master in Linguistics from Belgium (2006-2007), an MBA from Blekinge Institute of Technology in Sweden (2006-2008), and an Erasmus Mundus joint program European Master of Higher Education from universities in Norway, Finland, and Portugal (2009).
She is the founder of Fe/male Switch, a startup game that encourages women to enter STEM fields, and also leads CADChain, and multiple other projects like the Directory of 1,000 Startup Cities with a proprietary MeanCEO Index that ranks cities for female entrepreneurs. Violetta created the "gamepreneurship" methodology, which forms the scientific basis of her startup game. She also builds a lot of SEO tools for startups. Her achievements include being named one of the top 100 women in Europe by EU Startups in 2022 and being nominated for Impact Person of the year at the Dutch Blockchain Week. She is an author with Sifted and a speaker at different Universities. Recently she published a book on Startup Idea Validation the right way: from zero to first customers and beyond and launched a Directory of 1,500+ websites for startups to list themselves in order to gain traction and build backlinks.
