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Top 10 Cities for Deeptech Startups in South America in 2025
2025-04-25 10:32 Top 10

Top 10 Cities for Deeptech Startups in South America in 2025

Top 10 Cities for Deeptech Startups in South America in 2025

As deeptech continues to carve its path within the global innovation landscape, South America is increasingly becoming a hub for startups focused on disruptive technologies. In 2025, certain cities are expected to shine brighter than others, providing a fertile ground for entrepreneurial growth. Below is a detailed list of the Top 10 Cities for Deeptech Startups in South America in 2025, highlighting their unique strengths, key sectors, and relevant data.
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1. São Paulo, Brazil

Key Sectors: Fintech, E-commerce, Healthtech, Agritech, AI
Strengths: As the largest tech hub in Brazil and Latin America, São Paulo boasts a highly dynamic startup scene bolstered by extensive infrastructure and international investments. The city is renowned for its fintech industry and has a rich talent pool in cloud technology, AI, and blockchain.
Data Points:
  • The city is growing at a rate of around 10-15% annually.
  • Hosts numerous multinational companies, enhancing the innovation ecosystem.
  • It's recognized as a leader in both clean tech and fintech sectors.
  • Learn more about São Paulo's tech scene

2. Mexico City, Mexico

Key Sectors: Fintech, Software Development, E-commerce, AI
Strengths: Boasting a vibrant startup environment, Mexico City has over 700,000 IT professionals and attracts considerable international investment. Major tech players such as Google and Amazon have a presence here, and it is often referred to as the "Silicon Valley of Latin America."
Data Points:
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3. Buenos Aires, Argentina

Key Sectors: Fintech, Agritech, AI, Software Development
Strengths: Buenos Aires is recognized for its excellent tech talent and software development capabilities. The city is a significant player in the deeptech field, particularly in fintech and agritech.
Data Points:
  • Known for its well-educated IT professionals who have good English skills.
  • It leads in capital raised within the deep tech sector in Latin America.
  • Explore Buenos Aires tech talent

4. Guadalajara, Mexico

Key Sectors: Technology, Innovation, Software Development
Strengths: Often referred to as "Mexico's Silicon Valley," Guadalajara is recognized for its advanced tech infrastructure and a focus on innovation.
Data Points:

5. Santiago, Chile

Key Sectors: Cloud, IoT, Clean Energy
Strengths: Santiago has a highly educated workforce and is a well-resourced market focusing on Cloud and IoT technologies. It has received significant government support to promote innovation.
Data Points:
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6. Medellín, Colombia

Key Sectors: Software Development
Strengths: Medellín has evolved into a notable technological center with significant growth in its tech sector.
Data Points:

7. Bogotá, Colombia

Key Sectors: Software Development
Strengths: Bogotá is home to a vibrant startup culture with a skilled talent pool that drives its tech sector forward.
Data Points:

8. Lima, Peru

Key Sectors: Emerging Tech Ecosystem
Strengths: Lima is experiencing a growing tech ecosystem, supported by initiatives such as DEEPTECH BOOST 2025 LATAM.
Data Points:

9. Montevideo, Uruguay

Key Sectors: Tech Hub
Strengths: With government policies that support technology and innovation, Montevideo is emerging as a notable tech hub in the region.
Data Points:

10. Belo Horizonte, Brazil

Key Sectors: Technology
Strengths: Belo Horizonte is gaining traction in the tech industry and is attracting interest from major players, including Google, fostering a startup culture.
Data Points:
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FAQ

Q: Which city in South America is considered the primary tech hub?
A: São Paulo, Brazil, is recognized as the largest and most dynamic tech hub in Brazil and Latin America, hosting a robust infrastructure and a strong talent pool. Learn more about São Paulo's tech ecosystem.
Q: What makes Mexico City a leading city for startups?
A: Mexico City boasts a vibrant startup ecosystem with over 700,000 IT professionals, significant international investment, and the presence of major tech companies. Explore more about Mexico City's startup scene.
Q: What key sectors is Buenos Aires known for?
A: Buenos Aires, Argentina, specializes in fintech, agritech, and AI, with a strong talent pool that is well-educated and fluent in English. Discover Buenos Aires' strengths in technology.
Q: How is Guadalajara recognized within the tech community?
A: Guadalajara, Mexico is often referred to as "Mexico's Silicon Valley" due to its well-developed tech infrastructure and focus on innovation. Read more on Guadalajara's tech influence.
Q: What sectors are prominent in Santiago, Chile?
A: Santiago is making significant strides in cloud technology, IoT, and clean energy, supported by a highly educated workforce and government backing for innovation. Learn more about Santiago's tech progress.
Q: What is Medellín known for in terms of technology?
A: Medellín, Colombia has evolved into a technological center, showcasing a developing tech scene and significant technological advancements. Explore more about Medellín's growth.
Q: What is the description of Bogotá’s startup scene?
A: Bogotá, Colombia is characterized by its vibrant startup scene and skilled talent pool, contributing to its growth as a developing tech hub. Discover Bogotá's IT landscape.
Q: What initiatives are supporting the tech ecosystem in Lima, Peru?
A: Lima has a growing tech ecosystem and is the focus of a program called DEEPTECH BOOST 2025 LATAM, indicating its potential in deep tech innovation. Learn about Lima's tech initiatives.
Q: What are the key features of Montevideo's tech environment?
A: Montevideo, Uruguay is fostering a growing tech sector backed by pro-technology government policies, enhancing its position as an emerging tech hub. Read more about Montevideo's tech environment.
Q: Why is Belo Horizonte notable in the tech world?
A: Belo Horizonte, Brazil, is recognized for its growing tech presence and startup culture, attracting significant attention from tech giants like Google. Discover Belo Horizonte's tech culture.

About the Author

Violetta Bonenkamp, also known as MeanCEO, is an experienced startup founder with an impressive educational background including an MBA and four other higher education degrees. She has over 20 years of work experience across multiple countries, including 5 years as a solopreneur and serial entrepreneur.
Violetta is a true multiple specialist who has built expertise in Linguistics, Education, Business Management, Blockchain, Entrepreneurship, Intellectual Property, Game Design, AI, SEO, Digital Marketing, cyber security and zero code automations. Her extensive educational journey includes a Master of Arts in Linguistics and Education, an Advanced Master in Linguistics from Belgium (2006-2007), an MBA from Blekinge Institute of Technology in Sweden (2006-2008), and an Erasmus Mundus joint program European Master of Higher Education from universities in Norway, Finland, and Portugal (2009).
She is the founder of Fe/male Switch, a startup game that encourages women to enter STEM fields, and also leads CADChain, and multiple other projects like the Directory of 1,000 Startup Cities with a proprietary MeanCEO Index that ranks cities for female entrepreneurs. Violetta created the "gamepreneurship" methodology, which forms the scientific basis of her startup game. She also builds a lot of SEO tools for startups. Her achievements include being named one of the top 100 women in Europe by EU Startups in 2022 and being nominated for Impact Person of the year at the Dutch Blockchain Week. She is an author with Sifted and a speaker at different Universities. Recently she published a book on Startup Idea Validation the right way: from zero to first customers and beyond and launched a Directory of 1,500+ websites for startups to list themselves in order to gain traction and build backlinks.